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A multicentric, prospective, observational study evaluating the practice pattern and use of fixed dose topical regimen for hyperpigmentation in intimate and high friction areas

D. S. Krupa Shankar1*, Rajat Kandhari2, Sachin Varma3, Vijaya Bhaskar Mallela4, Rasya Dixit5, Rickson Pereira6

1 Mallige Hospital, Bangalore, Karnataka, India

2 Dr Kandhari's Skin & Dental Clinic, New Delhi, India

3 Skinvita Clinic, Kolkata, West Bengal, India

4 Omni Hospital, Hyderabad, Telangana, India

5 Dr. Dixit Cosmetic Dermatology, Bangalore, Karnataka, India

6 Dermatherapie Clinic, Mumbai, Maharashtra, India

September 2023

5 min read

Background: Hyperpigmentation is the third most common dermatological disorder and has major psychosocial impairment. It comes in a variety of forms. The most well-known are age spots, freckles, melasma and post-inflammatory hyperpigmentation. Hyperpigmentation in friction-prone areas (armpits, inner thighs, elbows, knees, groin, etc.) has a significant impact on affected individuals. Unfortunately, there are currently no well-tolerated options available that are intended particularly for these sensitive areas.

Methods: Dermatologists across India were provided a questionnaire consisting of questions related to number of the patients seen with hyperpigmentation in intimate & high friction areas every week and their clinical experience regarding the use of Pigmentbio Sensitive areas containing active ingredients (Andrographolide+Glabridin+Lysine azelate+Laminaria ochroleuca extract). The results were analyzed using a visual analogue scale.

Results: The study included a total of 1402 patients, and 75 dermatologists provided complete responses. The majority (96%) of the dermatologists recommended Pigmentbio Sensitive areas for intimate & high friction areas. These dermatologists also rated tolerability and safety of Pigmentbio Sensitive areas as "excellent" to "good" based on various criteria. These included tolerability after waxing and shaving the bikini line, soothing effect after mechanical erythema from taking off tight clothing, hydrating power when compared to other products, cosmetic acceptability for frictional and intimate areas, and safety on intimate areas.

Conclusions: This study findings indicated that Pigmentbio Sensitive areas is a preferred formulation by dermatologists across India for the management of hyperpigmentation in intimate & high friction areas with proven tolerability and safety.

Keywords: Hyperpigmentation, Intimate areas, High-friction areas, Study, Pigmentbio sensitive areas

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