Atoderm SOS spray

• Soothes itching sensations (-63 %*) in 60 seconds for 6 hours of efficacy ⁽¹⁾
• Reduces the urge to scratch from the first use (for 92% of patients) ⁽¹⁾
• Provides immediate and lasting comfort by reducing the release of pruritic mediators⁽¹⁾
• Provides an immediate sensation of freshness ⁽²⁾
• Very good tolerance - Non-comedogenic - Ultra-lightweight texture - Unfragranced - Ultra-fast 360° application in one easy step - Does not stain clothes

Clinically tested on patients with irritated, dry to very dry sensitive skin and patients suffering from itch (atopic skin, contact dermatitis, psoriasis, elderly people, children and pregnant women).

* p< 0.01, T-test, after D21

 (1) Evaluation of the efficacy and tolerance of Atoderm SOS Spray for 4 indications: psoriasis, chronic urticaria, senile pruritus and atopic dermatitis - 120 subjects aged 1 to 89 yo. 2016

(2) In vivo evaluation of reduction in TEWL after applying Atoderm SOS Spray – 12 female volunteers aged 34 to 70 years

> CLINICAL RESULTS

After 21 days of using Atoderm SOS spray as soon as necessary in patients with itching skin (due to psoriasis, chronic urticaria, senile pruritus and atopic dermatitis), a significant decrease of 63% in itching sensations was observed compared to D0.*(1)

Atoderm SOS Spray soothed itching within 60 seconds for 93% of patients and 56% of them said the anti-itching effect lasted at least 6 hours. (1)

The study shows also a significant decrease in:

• Itching duration (-39%) *
• Degree of itching (-34%) *
• Sleep disturbance (-46%) *
• Quality of life (49% improvement) *(1)

In children, regular application (2.5 times a day) of Atoderm SOS Spray for 21 days showed: (4)

• Skin dryness: – 52%*  
• Roughness: – 53%* 
• Desquamation: – 58%* 
• Skin suppleness: + 26%*

Two hours*, 8 hours** and even 12 hours* after a single application, Atoderm SOS Spray significantly reduced the Trans Epidermal Water Loss (TEWL) and therefore improved the barrier function. (2)

TOLERANCE
100% in adults (3). In babies and children (aged 8 months to 3 years), Atoderm SOS Spray was also very well-tolerated. (4)
* p< 0.01, T-test ** p≤0.05, T-test

> PATIENTS FEEDBACKS

Concerning patients suffering from cutaneous itching :

• 95% of them found that Atoderm SOS Spray provide a pleasant sensation of freshness(1)
• 86% of them found Atoderm SOS Spray fine and pleasant to spray (3)
• 90% of them found that Atoderm SOS Spray does not leave a greasy film (4)
• 95% of them would recommend the product and 96% said they wanted to keep using Atoderm SOS Spray. (4)

(1) Evaluation of the efficacy and tolerance of ATODERM SOS SPRAY for 4 indications: psoriasis, chronic urticaria, senile pruritus and atopic dermatitis - 120 subjects aged 1 to 89 years. 2016
(2) In vivo evaluation of reduction in TEWL after applying Atoderm SOS Spray – 12 female volunteers aged 34 to 70 years.
(3) Usage test under medical supervision - 22 volunteers aged 35 to 65 years (average age 53 years) with dry to very dry skin and cutaneous itching. Daily application to the body for 7 days, at least 3 times per day.
(4) Usage test under pediatric control - 17 volunteers aged 8 months to 3 years with reactive skin prone to atopy.