Management of different triggering factors effects in sensitive skin with a specific dermo-cosmetic product

After 28 days of product application, the product significantly improved skin barrier and presented a soothing effect whatever the triggering factor. In addition, up to 91% of Asiatic and Caucasian sensitive skin subjects judged the product efficient and the burden of sensitive skin significantly improved (BoSS score -14.1%). The product significantly reduced IL-1α after heat-cold stress at D0 (32.6%, p<0.001), and at D28 (27.7%, p<0.01) vs control. At D0 and D28, the S100A8/9 release with heat-cold stress was prevented by the product. Moreover, the product significantly improved hydration (up to +45%), and the global score (down to -50%) before and after heat-cold stress vs control.

Thus, the dermo-cosmetic product protected skin from mechanical, chemical, and heat-cold aggressions, in addition to pollution/UV previously studied. Through this innovative model, IL-1α and S100A8/9 seem to be relevant biomarkers to assess SSS.

Polena Helena, Fontbonne Arnaud, Abric Elise, Giraud Félix, Chavagnac Marlène, Graizeau Christelle, Ardiet Nathalie, Trompezinski Sandra, Sayag Michèle

NAOS Group, Aix-en-Provence, France

NAOS ILS, Aix-en-Provence, France